Hepatitis C: Viral kinetics

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Viral hepatitis C.

Hepatitis C is caused by the hepatitis C virus (HCV) infection. According to World Health Organization data, 3% of the world population (approximately 170 million people) is infected with HCV; in Poland there are over 700,000. Over 70% of those infected manifest no symptoms in the acute phase of the disease, and in about 70-80% the acute phase progresses into a chronic form. Patients with sympt...

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Effect of ribavirin on hepatitis C viral kinetics in patients treated with pegylated interferon.

A dynamic equilibrium between viral production and clearance characterizes untreated chronic hepatitis C viral infection. After initiating antiviral treatment, a typical multiphasic decay of viremia can be observed and analyzed using mathematical models. To elucidate the antiviral mechanism of ribavirin when used in combination with (pegylated) interferon alfa, we investigated kinetic parameter...

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Viral kinetics during the first month of treatment in patients with genotype 1 chronic hepatitis C.

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 Hepatitis C viral kinetics in Latino patients: a comparison to African American and Caucasian patients.

INTRODUCTION Response to hepatitis C treatment is known to differ by race; and, limited data suggests by ethnicity as well. A lower efficacy of HCV therapy in Latinos has been observed; whether higher doses may improve the response is unknown. MATERIAL AND METHODS This study used the available data from the patients enrolled in the PROGRESS study and stratified it by race and ethnicity. The p...

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ژورنال

عنوان ژورنال: Hepatology

سال: 1997

ISSN: 0270-9139,1527-3350

DOI: 10.1002/hep.510260651